Why has my Metformin quit working?
Posted on Jan 09, 2009 under insulin resistance symptoms | 2 CommentsI was put on 500 mg of Met on Dec. 6th. for PCOS and Insulin Resistance.It worked great for about a month, now it has quit working. All my symptoms that disappeared on Met have returned even though I am still taking it. Why? Am I supposed to be following a low carb diet with Met? My dr didn't say.
I know that Alabama Girl, but my doctor won't give me the go ahead to increase it. I have to wait a whole nother month and the pay for tests before she will let me increase. I'm afraid if I say it isn't working, she will take it away!
what is your current dose dose of glucophage…the typical dose is 500 mg twice a day. if you are already taking this your doctor may need to incorporate another med like prandin that you take before meals. if you have type 2 diabetes (your cells no longer respond to insulin), you should decrease your intake of carbohydrates and sugars, because the more insulin you are releasing the more resistant your cells are becoming.
powered by Yahoo Answers
January 9th, 2009 at 8:41 pm
I don't think you are taking enough Metformin.
Your doctor probably wants to check your liver function tests before upping the dosage:
What is lactic acidosis and can it happen to me?
Lactic acidosis is caused by a buildup of lactic acid in the blood. Lactic acidosis associated with GLUCOPHAGE is rare and has occurred mostly in people whose kidneys were not working normally. Lactic acidosis has been reported in about one in 33,000 patients taking GLUCOPHAGE over the course of a year. Although rare, if lactic acidosis does occur, it can be fatal in up to half the cases.
It's also important for your liver to be working normally when you take GLUCOPHAGE. Your liver helps remove lactic acid from your bloodstream.
Your doctor will monitor your diabetes and may perform blood tests on you from time to time to make sure your kidneys and your liver are functioning normally.
There is no evidence that GLUCOPHAGE causes harm to the kidneys or liver.
http://www.diabetesmonitor.com/metf-qa.htm
References :
January 9th, 2009 at 8:48 pm
what is your current dose dose of glucophage…the typical dose is 500 mg twice a day. if you are already taking this your doctor may need to incorporate another med like prandin that you take before meals. if you have type 2 diabetes (your cells no longer respond to insulin), you should decrease your intake of carbohydrates and sugars, because the more insulin you are releasing the more resistant your cells are becoming.
References :